Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT4+.
نویسندگان
چکیده
A biotinylated 1,5-dialkoxynaphthalene derivative has been shown to have the ability to bind strongly to avidin and thus act as an artificial binding site for cyclobis(paraquat-p-phenylene) thereby facilitating the formation of a tuneable pseudorotaxane-based bioconjugate.
منابع مشابه
Presentation of ligands on hydroxylapatite.
Conjugates of biotin with the decamer of glutamic acid (glu10) and the trimer of D,L-2-amino-5-phosphonovaleric acid (I) have been synthesized, and it has been shown that they mediate the binding of avidin to hydroxylapatite. In a similar way a conjugate of methotrexate with glu10 mediates the binding of dihydrofolate reducatase to the mineral. The presentation of ligands on the hydroxylapatite...
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عنوان ژورنال:
- Chemical communications
دوره 23 شماره
صفحات -
تاریخ انتشار 2008